STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV44715.1Hypothetical protein; COGs: COG1587 Uroporphyrinogen-III synthase; KEGG: lif:LinJ03.0300 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen-III synthase HemD. (272 aa)    
Predicted Functional Partners:
ADV42782.1
COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754; KEGG: bfs:BF0075 uroporphyrinogen-III synthase; PFAM: Uroporphyrinogen III synthase HEM4; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen-III synthase HemD.
     
  0.900
ADV44714.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
  
 0.808
ADV44713.1
COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638: IPR004558: IPR007197: IPR010723; KEGG: bfr:BF1914 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.768
ADV44711.1
TonB-dependent receptor plug; COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bfs:BF1986 putative outer membrane protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: Putative outer membrane protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain.
 
   
 0.760
ADV44712.1
Major facilitator superfamily MFS_1; InterPro IPR011701; KEGG: bfs:BF1985 putative transmembrane transporter protein; PFAM: major facilitator superfamily MFS_1; SPTR: Putative transmembrane transporter protein; PFAM: Major Facilitator Superfamily.
 
     0.759
ADV43377.1
Cytochrome c assembly protein; COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR002541; KEGG: bth:BT_2474 cytochrome c biogenesis protein CcsA; PFAM: cytochrome c assembly protein; SPTR: Putative uncharacterized protein; PFAM: ResB-like family; Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB.
  
    0.718
ADV44710.1
COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593: IPR003439; KEGG: bth:BT_1242 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; PFAM: ABC transporter.
       0.505
cbiD
Cobalamin (vitamin B12) biosynthesis CbiD protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
  
 0.482
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
       0.464
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
       0.453
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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