STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (343 aa)    
Predicted Functional Partners:
ADV44766.1
Thiamine pyrophosphate TPP-binding domain-containing protein; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
       0.727
ADV44767.1
Pyruvate/ketoisovalerate oxidoreductase, catalytic domain protein; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: bfs:BF1701 indolepyruvate oxidoreductase subunit beta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Putative uncharacterized protein; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit.
       0.727
ADV44768.1
phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
       0.684
ADV43676.1
Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264: IPR001460: IPR000634; KEGG: pru:PRU_0704 penicillin-binding protein 1A; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative uncharacterized protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
 
   
 0.592
ADV44410.1
Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264: IPR001460; KEGG: bfs:BF2276 putative penicillin-binding peptidoglycan biosynthesis-related exported protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative uncharacterized protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
  
   
 0.564
ADV44157.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
   
 0.555
ADV43257.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
   
 0.523
ADV43418.1
COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR013708: IPR006151; KEGG: bth:BT_4215 shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; SPTR: Putative uncharacterized protein; PFAM: Shikimate dehydrogenase substrate binding domain; TIGRFAM: shikimate 5-dehydrogenase.
  
    0.506
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.504
ADV43160.1
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182: IPR018365; KEGG: bfr:BF4096 rod shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Putative uncharacterized protein; PFAM: Cell cycle protein; Belongs to the SEDS family.
 
   
 0.500
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.