STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV44923.1Thioesterase superfamily protein; InterPro IPR006683; KEGG: bfs:BF3031 putative thioesterase; PFAM: thioesterase superfamily protein; SPTR: Putative uncharacterized protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1. (163 aa)    
Predicted Functional Partners:
ADV44924.1
L-fucose transporter; COGs: COG0738 Fucose permease; InterPro IPR005275: IPR011701; KEGG: bfs:BF0215 putative L-fucose permease; PFAM: major facilitator superfamily MFS_1; SPTR: Putative uncharacterized protein; TIGRFAM: L-fucose transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: L-fucose:H+ symporter permease.
       0.773
ADV44927.1
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: bfs:BF0213 putative aldolase; PFAM: class II aldolase/adducin family protein; SPTR: Putative uncharacterized protein; PFAM: Class II Aldolase and Adducin N-terminal domain.
  
  
 0.756
ADV44925.1
Protein of unknown function DUF718; COGs: COG3254 conserved hypothetical protein; InterPro IPR008000; KEGG: bth:BT_1276 hypothetical protein; PFAM: protein of unknown function DUF718; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF718).
 
     0.752
ADV44926.1
Carbohydrate kinase, FGGY; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: bfs:BF0214 putative fuculokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Putative uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain.
       0.720
ADV44928.1
Lactaldehyde reductase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR013460: IPR001670: IPR018211; KEGG: bfs:BF0212 L-1,2-propanediol oxidoreductase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Putative lactaldehyde reductase; TIGRFAM: lactaldehyde reductase; PFAM: Iron-containing alcohol dehydrogenase; TIGRFAM: lactaldehyde reductase.
       0.718
fucI
L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
       0.649
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
    0.640
hisG
ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.638
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR001917; KEGG: bth:BT_0202 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.604
hisB
COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterProIPR005954: IPR006543: IPR006549: IPR000807: IPR 020565; KEGG: bth:BT_0203 imidazole glycerol-phosphate dehydratase/histidinol phosphatase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Histidinol-phosphatase; SPTR: Putative uncharacterized protein; TIGRFAM: histidinol-phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Imidazoleglycerol-phosphate dehydratase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; histidinol-phosphate phosphatase family domain; [...]
       0.588
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.