STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADV45131.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198; KEGG: amu:Amuc_1001 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (276 aa)    
Predicted Functional Partners:
nuoC
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.847
ADV45132.1
KEGG: chy:CHY_1707 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    0.612
ADV43030.1
DEAD/DEAH box helicase domain protein; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR014021: IPR001650: IPR011545: IPR014001; KEGG: bvu:BVU_2638 ATP-dependent DNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative uncharacterized protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
    
 
 0.492
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 
 0.466
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.461
ADV45047.1
COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR020471: IPR001395; KEGG: bfs:BF2134 putative aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Putative uncharacterized protein; PFAM: Aldo/keto reductase family.
 
 
 0.438
ADV44846.1
COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: bfr:BF2086 putative aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Putative uncharacterized protein; PFAM: Aldo/keto reductase family.
 
 
 0.433
ADV43910.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455; KEGG: bvu:BVU_2422 pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; SMART: Rhodanese domain protein; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Rhodanese-like domain; [...]
  
 
 0.414
ADV42926.1
Carboxymuconolactone decarboxylase; COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR003779; KEGG: msu:MS2158 hypothetical protein; PFAM: Carboxymuconolactone decarboxylase; SPTR: Putative uncharacterized protein; PFAM: Cupin domain; Carboxymuconolactone decarboxylase family.
 
  
 0.411
ADV44326.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043: IPR016160: IPR004410; KEGG: bth:BT_0789 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
  
 
 0.401
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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