STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV45131.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198; KEGG: amu:Amuc_1001 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (276 aa)    
Predicted Functional Partners:
nuoC
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.927
ADV45132.1
KEGG: chy:CHY_1707 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    0.613
ADV42579.1
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.562
ADV44326.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043: IPR016160: IPR004410; KEGG: bth:BT_0789 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
  
 
 0.560
lpxC
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
  
 
 0.521
ADV43335.1
COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR013014: IPR004703; KEGG: bvu:BVU_1796 putative phosphotransferase enzyme II, C component; PFAM: PTS system Galactitol-specific IIC component; SPTR: Putative uncharacterized protein; PFAM: PTS system sugar-specific permease component.
  
    0.517
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.515
ADV42642.1
COGs: COG2365 Protein tyrosine/serine phosphatase; InterPro IPR004861: IPR016130: IPR000387; KEGG: bfs:BF0135 hypothetical protein; PFAM: tyrosine phosphatase; SPTR: Putative uncharacterized protein; PFAM: Tyrosine phosphatase family.
  
 
   0.513
ADV43138.1
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.487
ADV43030.1
DEAD/DEAH box helicase domain protein; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR014021: IPR001650: IPR011545: IPR014001; KEGG: bvu:BVU_2638 ATP-dependent DNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative uncharacterized protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
    
 
 0.478
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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