STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV45208.1FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027: IPR000815: IPR004099; KEGG: bth:BT_1542 putative pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain. (458 aa)    
Predicted Functional Partners:
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.777
ADV44405.1
Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR000842: IPR005946; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase.
   
 0.699
ADV45206.1
Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: bth:BT_2034 two-component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Putative uncharacterized protein; PFAM: Response regulator receiver domain.
 
 0.676
ADV45122.1
COGs: COG0281 Malic enzyme; InterPro IPR012301: IPR012302: IPR002505: IPR012188; KEGG: bvu:BVU_0245 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; SPTR: Putative uncharacterized protein; PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain.
  
  
 0.656
ADV45209.1
KEGG: bfr:BF3720 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.626
nuoC
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
  
 
 0.624
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
  
 0.618
ADV43124.1
Hypothetical protein; InterPro IPR017936; KEGG: pru:PRU_2156 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Redoxin.
  
 0.615
ADV45207.1
COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR017871: IPR003439: IPR003593; KEGG: bfs:BF3510 putative ABC transport system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; PFAM: ABC transporter.
  
    0.586
atpA-2
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
  
 
 0.559
Your Current Organism:
Bacteroides helcogenes
NCBI taxonomy Id: 693979
Other names: B. helcogenes P 36-108, Bacteroides helcogenes DSM 20613, Bacteroides helcogenes P 36-108, Bacteroides helcogenes str. P 36-108, Bacteroides helcogenes strain P 36-108
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