STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1-2CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (343 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.999
DFW101_1318
CRISPR-associated exonuclease Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
 
 0.999
DFW101_1315
CRISPR-associated protein Cas2.
  
 
 0.988
DFW101_1319
CRISPR-associated protein, Csd2 family.
 
   
 0.955
DFW101_1321
CRISPR-associated protein Cas5 family.
 
   
 0.953
DFW101_1320
CRISPR-associated protein, Csd1 family.
 
   
 0.950
DFW101_1322
Metal dependent phosphohydrolase.
 
  
 0.897
DFW101_0442
Histone family protein DNA-binding protein; Belongs to the bacterial histone-like protein family.
    
   0.693
DFW101_0926
Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
   0.693
DFW101_1808
Histone family protein DNA-binding protein; Belongs to the bacterial histone-like protein family.
    
   0.693
Your Current Organism:
Desulfovibrio carbinoliphilus
NCBI taxonomy Id: 694327
Other names: D. carbinoliphilus subsp. oakridgensis, Desulfovibrio carbinoliphilus subsp. oakridgensis, Desulfovibrio sp. FW-101-2B, personal::FW-101-2B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.