STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DFW101_1627Cysteine desulfurase. (373 aa)    
Predicted Functional Partners:
DFW101_1117
Nitrogen fixation protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 0.996
DFW101_2894
Nitrogen-fixing NifU domain protein.
  
 0.993
DFW101_1616
Endonuclease/exonuclease/phosphatase.
 
 
   0.933
DFW101_0790
SufBD protein.
  
 
 0.924
DFW101_0791
ABC transporter related protein.
 
  
 0.922
DFW101_3117
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
    
 0.748
DFW101_1116
Cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
 
  
0.742
DFW101_1614
L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
 
 
  0.737
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.719
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
    
 0.712
Your Current Organism:
Desulfovibrio carbinoliphilus
NCBI taxonomy Id: 694327
Other names: D. carbinoliphilus subsp. oakridgensis, Desulfovibrio carbinoliphilus subsp. oakridgensis, Desulfovibrio sp. FW-101-2B, personal::FW-101-2B
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.