STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
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Textmining
[Homology]
Score
ADQ78232.1Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR018060: IPR005467: IPR001789: IPR011110: IPR 011123: IPR003661: IPR003594: IPR000005: IPR004358: IPR018062; KEGG: bth:BT_0267 two-component system sensor histidine kinase/response regulator, hybrid ('one component system'); PFAM: ATP-binding region ATPase domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC [...] (1346 aa)    
Predicted Functional Partners:
ADQ80770.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767: IPR003661: IPR003594: IPR001789: IPR 004358: IPR000014: IPR001610: IPR005467: IPR000700; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: Sensory transduc [...]
 
 
0.999
ADQ80307.1
COGs: COG4585 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 013767: IPR003018: IPR011712: IPR003594: IPR001610; KEGG: nde:NIDE1491 putative hybrid sensor histidine kinase; PFAM: response regulator receiver; PAS fold domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; GAF domain protein; ATP-binding region ATPase domain protein; SPTR: Multi-sensor signal transd [...]
 
 
0.988
ADQ80684.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110: IPR011123: IPR003661: IPR003594: IPR 001789: IPR000005: IPR004358: IPR005829: IPR018060: IPR005467; KEGG: bth:BT_1734 two-component system sensor histidine kinase/response regulator, hybrid ('one component system'); PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC [...]
 
 
0.976
ADQ80005.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR001789: IPR018060: IPR 005467: IPR011110: IPR000005: IPR004358: IPR018247: IPR018062; KEGG: bfs:BF3155 putative two-component system sensor kinase/response regulator fusion protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain prot [...]
 
 
0.975
ADQ79779.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR018060: IPR005467: IPR001789: IPR 003661: IPR003594: IPR018062: IPR011110: IPR011123: IPR000005; KEGG: zpr:ZPR_2934 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain p [...]
 
 
0.973
ADQ80258.1
Two component transcriptional regulator, AraC family; COGs: COG5002 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR001789: IPR018060: IPR 005467: IPR011110: IPR011123: IPR000005: IPR004358: IPR018062; KEGG: pdi:BDI_3101 two-component system sensor histidine kinase/response regulator, hybrid; PFAM: ATP-binding region ATPase domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: respons [...]
 
 
0.972
ADQ80302.1
COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR005467: IPR000014: IPR000700: IPR013767: IPR 013655: IPR003661: IPR003594: IPR004358: IPR001610; KEGG: ppd:Ppro_0091 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; SPTR: PAS/PAC sensor signal transduction h [...]
 
 
0.967
ADQ80306.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003660: IPR003018: IPR 003661: IPR003594: IPR004358; KEGG: gem:GM21_1722 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; GAF domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; GAF domain protein; response regulator receiver; SPTR: Histidine kinase; PFAM: HAMP domain; GAF domain; Histid [...]
 
 
0.945
ADQ80304.1
Putative PAS/PAC sensor protein; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789: IPR000014: IPR000700: IPR013767: IPR 013655: IPR013656: IPR001610: IPR022272; KEGG: dol:Dole_0981 PAS/PAC sensor hybrid histidine kinase; PFAM: response regulator receiver; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Respo [...]
 
 
 0.932
ADQ78530.1
COGs: COG4585 Signal transduction histidine kinase; InterProIPR005467: IPR000014: IPR000700: IPR001610: IPR 003594: IPR018771: IPR013656: IPR013655: IPR013767: IPR011712; KEGG: nde:NIDE3092 putative sensor histidine kinase; PFAM: Transcription regulator,histidine kinase sensor-like; PAS fold-4 domain protein; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Multi-sensor [...]
  
 
 0.920
Your Current Organism:
Paludibacter propionicigenes
NCBI taxonomy Id: 694427
Other names: P. propionicigenes WB4, Paludibacter propionicigenes CCUG 53888, Paludibacter propionicigenes DSM 17365, Paludibacter propionicigenes JCM 13257, Paludibacter propionicigenes WB4, Paludibacter propionicigenes str. WB4, Paludibacter propionicigenes strain WB4
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