STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ79423.1DNA topoisomerase III; COGs: COG0550 Topoisomerase IA; InterProIPR005738: IPR006154: IPR003601: IPR003602: IPR 000380: IPR006171: IPR013497; KEGG: bfs:BF3590 putative DNA topoisomerase; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: DNA topoisomerase III; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid. (639 aa)    
Predicted Functional Partners:
ADQ78783.1
HRDC domain protein; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR002121: IPR003593; KEGG: dps:DP1987 5'-3' DNA helicase; PFAM: HRDC domain protein; SMART: HRDC domain protein; AAA ATPase; SPTR: Putative helicase; PFAM: PIF1 helicase; HRDC domain.
 
 0.938
ADQ79999.1
COGs: COG0514 Superfamily II DNA helicase; InterProIPR014001: IPR001650: IPR002121: IPR014021: IPR 011545: IPR018982: IPR006293: IPR018329; KEGG: pdi:BDI_2394 ATP-dependent DNA helicase RecQ; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; RQC domain; HRDC domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: [...]
 
 0.880
ADQ80953.1
COGs: COG0514 Superfamily II DNA helicase; InterProIPR014001: IPR001650: IPR011545: IPR018329: IPR 014021; KEGG: pdi:BDI_1747 ATP-dependent DNA helicase RecQ; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family.
 
 0.867
ADQ79253.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: aps:CFPG_312 glutamate synthase large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.672
ADQ81048.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.616
ADQ78531.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900: IPR011894; KEGG: bfs:BF3168 putative pyruvate-flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate:ferredoxin (Flavodoxin) oxidoreductase; TIGRFAM: pyruvate ferredoxin/ [...]
  
   0.567
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.553
ADQ79521.1
Hypothetical protein; InterPro IPR022272; KEGG: chu:CHU_3583 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3127).
  
 
 0.548
ADQ79422.1
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterPro IPR001431: IPR011765: IPR007863; KEGG: bvu:BVU_1269 putative zinc protease; PFAM: peptidase M16 domain protein; SPTR: Putative uncharacterized protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.
       0.536
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.506
Your Current Organism:
Paludibacter propionicigenes
NCBI taxonomy Id: 694427
Other names: P. propionicigenes WB4, Paludibacter propionicigenes CCUG 53888, Paludibacter propionicigenes DSM 17365, Paludibacter propionicigenes JCM 13257, Paludibacter propionicigenes WB4, Paludibacter propionicigenes str. WB4, Paludibacter propionicigenes strain WB4
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