STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
ADQ79150.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872: IPR015590: IPR016160; KEGG: bvu:BVU_3604 putative proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydraogenase; PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; SPTR: Putative uncharacterized protein; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
 
 0.940
ADQ79253.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: aps:CFPG_312 glutamate synthase large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
    
 0.891
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
 
    
 0.861
ADQ78352.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR014362: IPR006097: IPR006096: IPR006095; KEGG: bfs:BF3437 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: NAD-specific glutamate dehydrogenase 1; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.831
ADQ79254.1
Glutamate synthase (NADH) small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006005; KEGG: aps:CFPG_313 glutamate synthase small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase small subunit; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit.
    
 0.811
ADQ80942.1
COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR006004: IPR000759; KEGG: pdi:BDI_3682 putative NADPH-dependent glutamate synthase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative uncharacterized protein; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric.
    
 0.811
ADQ79252.1
L-glutamine synthetase; COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: aps:CFPG_521 glutamine synthetase; PFAM: glutamine synthetase catalytic region; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase type III N terminal.
     
  0.800
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.738
ADQ79844.1
Peptidase M28; InterPro IPR007484; KEGG: bvu:BVU_1317 leucine aminopeptidase precursor; PFAM: peptidase M28; SPTR: Leucine aminopeptidase; PFAM: Peptidase family M28.
       0.714
Your Current Organism:
Paludibacter propionicigenes
NCBI taxonomy Id: 694427
Other names: P. propionicigenes WB4, Paludibacter propionicigenes CCUG 53888, Paludibacter propionicigenes DSM 17365, Paludibacter propionicigenes JCM 13257, Paludibacter propionicigenes WB4, Paludibacter propionicigenes str. WB4, Paludibacter propionicigenes strain WB4
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