STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADQ80149.1Transcriptional regulator; InterPro IPR001387: IPR013096; KEGG: bth:BT_3756 transcriptional regulator; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Putative uncharacterized protein; PFAM: Cupin domain; Helix-turn-helix. (182 aa)    
Predicted Functional Partners:
ADQ80148.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873: IPR020845; KEGG: bth:BT_3755 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetyl-coenzyme A synthetase; PFAM: AMP-binding enzyme.
 
 0.990
ADQ80630.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: bth:BT_2782 AMP-binding domain protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative uncharacterized protein; PFAM: AMP-binding enzyme.
 
  
 0.735
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
    0.623
ADQ81122.1
Protein of unknown function DUF955; COGs: COG2856 Zn peptidase; InterPro IPR001387: IPR010359; KEGG: cch:Cag_0309 hypothetical protein; PFAM: protein of unknown function DUF955; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF955).
  
  
 0.537
ADQ79150.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872: IPR015590: IPR016160; KEGG: bvu:BVU_3604 putative proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydraogenase; PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; SPTR: Putative uncharacterized protein; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
 
  
 0.536
cobB
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: pdi:BDI_2710 NAD-dependent deacetylase; PFAM: Silent information regulator protein Sir2; SPTR: NAD-dependent deacetylase (Regulatory protein SIR2-like protein); PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
    0.461
ADQ78232.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR018060: IPR005467: IPR001789: IPR011110: IPR 011123: IPR003661: IPR003594: IPR000005: IPR004358: IPR018062; KEGG: bth:BT_0267 two-component system sensor histidine kinase/response regulator, hybrid ('one component system'); PFAM: ATP-binding region ATPase domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC [...]
  
 
 0.431
ADQ80005.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR001789: IPR018060: IPR 005467: IPR011110: IPR000005: IPR004358: IPR018247: IPR018062; KEGG: bfs:BF3155 putative two-component system sensor kinase/response regulator fusion protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain prot [...]
  
 
 0.431
ADQ80684.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110: IPR011123: IPR003661: IPR003594: IPR 001789: IPR000005: IPR004358: IPR005829: IPR018060: IPR005467; KEGG: bth:BT_1734 two-component system sensor histidine kinase/response regulator, hybrid ('one component system'); PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator three Y domain-containing protein; Two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC [...]
  
 
 0.431
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.430
Your Current Organism:
Paludibacter propionicigenes
NCBI taxonomy Id: 694427
Other names: P. propionicigenes WB4, Paludibacter propionicigenes CCUG 53888, Paludibacter propionicigenes DSM 17365, Paludibacter propionicigenes JCM 13257, Paludibacter propionicigenes WB4, Paludibacter propionicigenes str. WB4, Paludibacter propionicigenes strain WB4
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