Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM38937.1Creatininase; PFAM: Creatinine amidohydrolase; KEGG: iho:Igni_0515 hypothetical protein; SPTR: Putative uncharacterized protein. (223 aa)    
Predicted Functional Partners:
AEM39223.1
PFAM: Glycosyl transferase family 2; COGs: COG1893 Ketopantoate reductase; InterPro IPR003710:IPR013332:IPR013752; KEGG: mpd:MCP_2660 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein; PRIAM: 2-dehydropantoate 2-reductase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase.
  
  
 0.751
AEM38449.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
       0.748
AEM39014.1
PEGA domain protein; KEGG: gbe:GbCGDNIH1_0097 cobalt-zinc-cadmium resistance protein CzcD; SPTR: Methyltransferase type 11.
       0.748
AEM38936.1
PFAM: Pyridine nucleotide-disulfide oxidoreductase; Pyridine nucleotide-disulfide oxidoreductase, dimerisation domain; COGs: COG1402 Uncharacterized protein putative amidase; InterPro IPR003785; KEGG: ape:APE_0954 hypothetical protein; PFAM: Creatininase; SPTR: Putative uncharacterized protein.
     
 0.456
AEM38471.1
PFAM: Ribose 5-phosphate isomerase A (phosphoriboisomerase A); TIGRFAM: ribose 5-phosphate isomerase; InterPro IPR007527; KEGG: hbu:Hbut_1090 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.417
Your Current Organism:
Pyrolobus fumarii
NCBI taxonomy Id: 694429
Other names: P. fumarii 1A, Pyrolobus fumarii 1A, Pyrolobus fumarii DSM 11204
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