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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl22Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (156 aa)    
Predicted Functional Partners:
rps19e
Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
   
 
 0.999
eif5a
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
   
 
 0.999
rpl21e
PFAM: Ribosomal protein L21e; COGs: COG1460 conserved hypothetical protein; InterPro IPR005574; KEGG: hbu:Hbut_1659 DNA-directed RNA polymerase, subunit F; PFAM: RNA polymerase Rpb4; SPTR: DNA-directed RNA polymerase, subunit F; Belongs to the eukaryotic ribosomal protein eL21 family.
   
 0.999
rpl10e
PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L10.e; COGs: COG1736 Diphthamide synthase subunit DPH2; InterPro IPR002728; KEGG: hbu:Hbut_1652 hypothetical protein; PFAM: Diphthamide synthesis DPH2 protein; SPTR: conserved archaeal protein; TIGRFAM: diphthamide biosynthesis protein; Belongs to the universal ribosomal protein uL16 family.
  
 0.999
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
   
 0.999
rpl30e
PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; COGs: COG0195 Transcription elongation factor; InterPro IPR004087:IPR010212:IPR004044; KEGG: hbu:Hbut_1577 putative transcription elongation factor; PFAM: KH type 2 domain protein; SMART: KH domain protein; SPTR: Putative transcription elongation factor; TIGRFAM: NusA family KH domain protein; Belongs to the eukaryotic ribosomal protein eL30 family.
   
  0.999
rps12
Ribosomal protein S23 (S12); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
  
 
 0.999
rps7
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.999
rps10
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.999
rps6e
PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 
 0.999
Your Current Organism:
Pyrolobus fumarii
NCBI taxonomy Id: 694429
Other names: P. fumarii 1A, Pyrolobus fumarii 1A, Pyrolobus fumarii DSM 11204
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