STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB37715.1methionine-R-sulfoxide reductase; IMG reference gene:2506730641; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. (128 aa)    
Predicted Functional Partners:
msrA
methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.987
AGB36208.1
IMG reference gene:2506729058; PFAM: Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase.
 
 0.982
AGB39358.1
Catalase; IMG reference gene:2506732358; PFAM: Catalase; DJ-1/PfpI family; Catalase-related immune-responsive.
  
 
 0.785
AGB37714.1
Hypothetical protein; IMG reference gene:2506730640.
       0.642
grpE
Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
   
 
 0.630
AGB37167.1
Thioredoxin reductase; IMG reference gene:2506730069; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Glutaredoxin; TIGRFAM: thioredoxin-disulfide reductase; Glutaredoxin, GrxC family.
  
  
 0.628
AGB37716.1
Hypothetical protein; IMG reference gene:2506730642; PFAM: Uncharacterized conserved protein (DUF2196).
       0.565
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
     
 0.556
AGB39421.1
acyl-CoA synthetase/AMP-acid ligase; IMG reference gene:2506732422; PFAM: Domain of unknown function (DUF3448); Enoyl-CoA hydratase/isomerase family; AMP-binding enzyme; Zinc-binding dehydrogenase.
  
  
 0.543
AGB37364.1
Thiol-disulfide isomerase-like thioredoxin; IMG reference gene:2506730273; PFAM: Thioredoxin.
   
 0.514
Your Current Organism:
Natronococcus occultus
NCBI taxonomy Id: 694430
Other names: N. occultus SP4, Natronococcus occultus DSM 3396, Natronococcus occultus SP4, Natronococcus occultus str. SP4, Natronococcus occultus strain SP4
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.