STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nnrDyjeF-like protein, hydroxyethylthiazole kinase-related protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (258 aa)    
Predicted Functional Partners:
AGB37724.1
Methylase involved in ubiquinone/menaquinone biosynthesis; IMG reference gene:2506730650; PFAM: Methyltransferase domain.
  
    0.608
nnrE
yjeF-like protein, hydroxyethylthiazole kinase-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate d [...]
  
  
 
0.593
AGB37722.1
Putative phosphoribosyltransferase; IMG reference gene:2506730648; PFAM: Phosphoribosyl transferase domain.
       0.547
AGB37725.1
Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; IMG reference gene:2506730651; PFAM: Aminotransferase class-V.
       0.495
AGB36847.1
IMG reference gene:2506729716; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
       0.453
AGB37215.1
Flavin-dependent dehydrogenase; IMG reference gene:2506730119; PFAM: FAD binding domain.
  
    0.451
AGB38391.1
Putative copper export protein; IMG reference gene:2506731345; PFAM: Copper resistance protein CopC; Copper resistance protein D.
 
     0.442
AGB39080.1
IMG reference gene:2506732063; PFAM: Phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor-related protein.
 
    0.403
AGB38903.1
Chaperonin GroEL; IMG reference gene:2506731879; PFAM: TCP-1/cpn60 chaperonin family; manually curated; Belongs to the TCP-1 chaperonin family.
 
    0.400
AGB39681.1
Ammonia permease; IMG reference gene:2506732699; PFAM: Ammonium Transporter Family; Nitrogen regulatory protein P-II; TIGRFAM: ammonium transporter; Belongs to the P(II) protein family.
       0.400
Your Current Organism:
Natronococcus occultus
NCBI taxonomy Id: 694430
Other names: N. occultus SP4, Natronococcus occultus DSM 3396, Natronococcus occultus SP4, Natronococcus occultus str. SP4, Natronococcus occultus strain SP4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.