STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB37792.1Deoxyhypusine synthase; IMG reference gene:2506730722; PFAM: Deoxyhypusine synthase; TIGRFAM: deoxyhypusine synthase. (347 aa)    
Predicted Functional Partners:
eif5a
Translation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
 
 0.884
flpA
Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
   0.581
AGB37793.1
Hypothetical protein; IMG reference gene:2506730723.
       0.529
pheS
phenylalanyl-tRNA synthetase, alpha subunit; IMG reference gene:2506731223; PFAM: tRNA synthetases class II core domain (F); TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
  
  
 0.524
rpl6
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.501
AGB37794.1
Dinuclear metal center protein, YbgI/SA1388 family; IMG reference gene:2506730724; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family.
   
   0.487
rps7
Ribosomal protein S7/S5; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
  
    0.485
rpoD
DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
 
    0.449
rpl10e
Ribosomal protein L16/L10E; IMG reference gene:2506728901; PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L10.e; manually curated; Belongs to the universal ribosomal protein uL16 family.
 
    0.447
tiaS
Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
     
 0.442
Your Current Organism:
Natronococcus occultus
NCBI taxonomy Id: 694430
Other names: N. occultus SP4, Natronococcus occultus DSM 3396, Natronococcus occultus SP4, Natronococcus occultus str. SP4, Natronococcus occultus strain SP4
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