Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AHF97830.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (114 aa)    
Predicted Functional Partners:
AHF96813.1
Ankyrin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.904
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.895
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
 
 
 0.823
AHF96895.1
Peptidase M24; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.810
AHF97587.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.809
AHF96897.1
Nitrogenase iron-molybdenum cofactor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.786
groEL
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.781
AHF96896.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.738
AHF96898.1
Nitrogen regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.729
AHF97831.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.725
Your Current Organism:
Desulfurella acetivorans
NCBI taxonomy Id: 694431
Other names: D. acetivorans A63, Desulfurella acetivorans A63, Desulfurella acetivorans DSM 5264, Desulfurella acetivorans str. A63, Desulfurella acetivorans strain A63
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