STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7P421_IXOSCHeparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (304 aa)    
Predicted Functional Partners:
B7PYQ5_IXOSC
D-glucuronyl C5-epimerase, putative (Fragment).
    
 
 0.728
B7P6T4_IXOSC
Heparan sulfate 2-O-sulfotransferase, putative.
    
 
 0.711
B7PJC6_IXOSC
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.708
B7PP95_IXOSC
Heparan sulfate sulfotransferase, putative (Fragment).
      
 0.695
B7PRN4_IXOSC
Heparan sulfate sulfotransferase, putative.
      
 0.695
B7PRT4_IXOSC
Glypican, putative (Fragment); Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.660
B7PAN2_IXOSC
Sulfatase-1, sulf-1, putative (Fragment).
    
 
 0.642
B7QII2_IXOSC
Heparan sulfate N-deacetylase/N-sulfotransferase, putative (Fragment).
      
 0.632
B7QCU1_IXOSC
Exostosin-3, putative; Belongs to the glycosyltransferase 47 family.
      
 0.580
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
Server load: low (26%) [HD]