STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7PA62_IXOSCHeat shock protein 70 (HSP70)-interacting protein, putative. (430 aa)    
Predicted Functional Partners:
B7P217_IXOSC
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.690
B7PL67_IXOSC
ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
   
 0.547
B7Q634_IXOSC
Cap binding protein, putative.
    
 0.543
B7QER9_IXOSC
DEAD box ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.
   
 0.535
Cbp20
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...]
    
 0.526
B7PWB9_IXOSC
Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.
   
 0.504
B7PU75_IXOSC
MPN domain-containing protein, putative.
   
 0.503
B7PTI1_IXOSC
Small nuclear ribonucleoprotein G.
   
 0.498
B7Q7I2_IXOSC
Eukaryotic translation initiation factor 2 gamma subunit, putative.
   
 0.495
B7PQ08_IXOSC
U1 small nuclear ribonucleoprotein A, putative.
    
 0.486
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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