STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7PHN8_IXOSCHistone transcription regulator, putative. (643 aa)    
Predicted Functional Partners:
B7QIN7_IXOSC
Anti-silencing protein, putative.
    
 0.998
B7Q8R8_IXOSC
TPR_REGION domain-containing protein.
    
 0.890
B7Q8R9_IXOSC
Uncharacterized protein.
    
 0.890
B7P2S5_IXOSC
Retinoblastoma-binding protein, putative (Fragment).
    
 
 0.741
Q4PM69_IXOSC
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.651
B7P7T4_IXOSC
Histone H3; Belongs to the histone H3 family.
    
 
 0.641
B7PAJ2_IXOSC
Histone H3; Belongs to the histone H3 family.
    
 
 0.641
B7PCF3_IXOSC
Histone H3, putative.
    
 
 0.641
B7QLN0_IXOSC
Insilun induced protein.
    
 
 0.584
B7PBP0_IXOSC
Histone H3, putative.
    
 
 0.578
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.