STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7Q4B4_IXOSCHistidine triad (Hit) protein member, putative. (334 aa)    
Predicted Functional Partners:
B7PTZ6_IXOSC
Pacman protein, putative.
    
 
 0.729
B7P278_IXOSC
mRNA-decapping enzyme, putative; Belongs to the Nudix hydrolase family.
   
  
 0.684
B7Q688_IXOSC
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family.
 
    
 0.630
B7QH01_IXOSC
5'->3' exoribonuclease, putative (Fragment).
   
  
 0.589
B7QA69_IXOSC
tRNA-splicing endonuclease subunit Sen2, putative.
      
 0.574
B7QF29_IXOSC
Ribosomal DEAD box protein, putative (Fragment); Belongs to the DEAD box helicase family.
   
  
 0.572
B7PUR0_IXOSC
AD domain-containing protein.
      
 0.536
B7PGM8_IXOSC
Sulfite-dehydrogenase, putative (Fragment); Belongs to the cytochrome b5 family.
    
   0.508
B7QEI9_IXOSC
60S ribosomal protein L3, putative; Belongs to the universal ribosomal protein uL3 family.
      
 0.482
B7P467_IXOSC
RNA polymerase III (Fragment); Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
 
 
    0.467
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.