STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7Q988_IXOSCDNA polymerase theta, putative (Fragment). (704 aa)    
Predicted Functional Partners:
B7PSI7_IXOSC
Uncharacterized protein.
   
 
 0.818
B7PSI8_IXOSC
ERCC4 domain-containing protein.
   
 
 0.818
B7QH20_IXOSC
Uncharacterized protein.
   
 
 0.818
B7Q1M0_IXOSC
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.790
B7P5X1_IXOSC
Fanconi anemia group D2 protein, putative (Fragment).
   
 0.717
B7P981_IXOSC
Exonuclease, putative (Fragment).
  
 
 0.689
B7P983_IXOSC
Exonuclease, putative.
  
 
 0.689
B7P1K3_IXOSC
SMC protein, putative (Fragment).
  
 
 0.666
B7PMU3_IXOSC
DNA-repair protein xp-G, putative (Fragment).
  
 
 0.659
B7PVF3_IXOSC
Peptide methionine sulfoxide reductase, putative (Fragment).
  
  
 0.647
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.