STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7QE05_IXOSCRest corepressor (Corest) protein, putative. (104 aa)    
Predicted Functional Partners:
B7PJ47_IXOSC
Lysine-specific histone demethylase, putative.
    
 0.856
B7PX42_IXOSC
Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.
    
 0.856
B7P990_IXOSC
Uncharacterized protein.
   
 0.820
B7PLQ0_IXOSC
Chromodomain helicase DNA binding protein, putative.
    
 0.806
B7PVH5_IXOSC
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.791
B7PS10_IXOSC
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.672
B7QFL9_IXOSC
Histone deacetylase 1, 2, 3, putative.
    
 0.672
B7Q088_IXOSC
Histone deacetylase, putative.
    
 0.669
B7QMT6_IXOSC
Amine oxidase, putative (Fragment).
   
 0.660
B7QHP0_IXOSC
Sap18, putative (Fragment).
     
 0.626
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.