STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7QE95_IXOSCNucleoside diphosphate kinase. (74 aa)    
Predicted Functional Partners:
B7P697_IXOSC
Deoxycytidine triphosphate deaminase.
  
 
 0.985
B7Q0D8_IXOSC
Thymidylate kinase, putative.
  
 
 0.985
B7Q0D7_IXOSC
Guanosine polyphosphate pyrophosphohydrolase/synthase, putative (Fragment).
    
 0.983
B7QGF4_IXOSC
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 0.983
B7PTS6_IXOSC
AAA domain-containing protein.
    
 0.982
B7Q5M1_IXOSC
Guanylate kinase, putative.
  
 0.975
B7Q668_IXOSC
Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative.
   
 
 0.964
B7Q1F8_IXOSC
28S ribosomal protein S15, putative.
  
 0.958
B7P674_IXOSC
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
 0.957
B7P7Z6_IXOSC
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
 0.957
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.