STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7QJ45_IXOSCHistone deacetylase 4, 5, putative (Fragment). (900 aa)    
Predicted Functional Partners:
B7P696_IXOSC
Sensory transduction histidine kinase, putative (Fragment).
    
 0.938
B7PV64_IXOSC
RNA polymerase-associated protein LEO1, putative.
    
 0.930
B7P2S5_IXOSC
Retinoblastoma-binding protein, putative (Fragment).
   
 0.813
B7Q472_IXOSC
Sin3b, putative (Fragment).
    
 0.798
B7P5E7_IXOSC
Uncharacterized protein.
    
 0.760
Q4PM69_IXOSC
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.754
B7PZ26_IXOSC
Myb family DNAbinding domain-containing protein.
    
 0.739
B7P8U5_IXOSC
Nuclear pore complex protein nup155, putative (Fragment).
   
 0.725
B7P3N5_IXOSC
Ran-binding protein (RanBP), putative.
   
 0.705
B7PS10_IXOSC
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
  
 
 
0.682
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.