STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7QLS8_IXOSCPhosphodiesterase. (849 aa)    
Predicted Functional Partners:
B7PHX7_IXOSC
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
     
 0.924
B7Q4L2_IXOSC
Adenylate cyclase, putative (Fragment); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.919
B7P9V2_IXOSC
Adenylate cyclase, putative (Fragment); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.917
B7Q9S7_IXOSC
Adenylate cyclase, putative (Fragment).
    
 0.917
B7PXV5_IXOSC
Adenosine monophosphate deaminase, putative (Fragment).
     
 0.915
B7Q8U6_IXOSC
Adenosine kinase, putative.
     
 0.915
B7PTS0_IXOSC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
    
 0.912
B7PHR1_IXOSC
ATP diphosphohydrolase apyrase, putative.
     
 0.910
B7Q3A0_IXOSC
Adenylate kinase, putative (Fragment); Belongs to the adenylate kinase family.
     
 0.910
B7QDE2_IXOSC
RB13-6 antigen, putative (Fragment).
    
 0.910
Your Current Organism:
Ixodes scapularis
NCBI taxonomy Id: 6945
Other names: I. scapularis, Ixodes dammini, Ixodes sp. DNAS-303-249710, black-legged tick, blacklegged tick, deer tick, shoulder tick
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.