pepA protein (Bartonella clarridgeiae) - STRING interaction network

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Score

pepA

Leucyl aminopeptidase; Belongs to the peptidase M17 family. (460 aa)

Predicted Functional Partners:

gshB

0.932

pepN

0.932

gshA

0.900

aatA

0.831

glyA

0.812

coaA

0.752

BARCL_0146

0.620

polA

0.522

ansA

0.506

gcvP

0.499

Your Current Organism:

Bartonella clarridgeiae

NCBI taxonomy Id: 696125
Other names: B. clarridgeiae 73, Bartonella clarridgeiae 73, Bartonella clarridgeiae str. 73, Bartonella clarridgeiae strain 73

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BARCL_0146	coaA	BARCL_0146	BARCL_0148	Homologs of previously reported genes of unknown function.	Pantothenate kinase.	0.487
BARCL_0146	pepA	BARCL_0146	BARCL_0147	Homologs of previously reported genes of unknown function.	Leucyl aminopeptidase; Belongs to the peptidase M17 family.	0.620
aatA	ansA	BARCL_0344	BARCL_0149	Aspartate aminotransferase A.	L-asparaginase.	0.923
aatA	gcvP	BARCL_0344	BARCL_0507	Aspartate aminotransferase A.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.460
aatA	gshA	BARCL_0344	BARCL_0242	Aspartate aminotransferase A.	Glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.	0.800
aatA	pepA	BARCL_0344	BARCL_0147	Aspartate aminotransferase A.	Leucyl aminopeptidase; Belongs to the peptidase M17 family.	0.831
aatA	pepN	BARCL_0344	BARCL_0399	Aspartate aminotransferase A.	Aminopeptidase N.	0.801
ansA	aatA	BARCL_0149	BARCL_0344	L-asparaginase.	Aspartate aminotransferase A.	0.923
ansA	coaA	BARCL_0149	BARCL_0148	L-asparaginase.	Pantothenate kinase.	0.488
ansA	gcvP	BARCL_0149	BARCL_0507	L-asparaginase.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.442
ansA	pepA	BARCL_0149	BARCL_0147	L-asparaginase.	Leucyl aminopeptidase; Belongs to the peptidase M17 family.	0.506
coaA	BARCL_0146	BARCL_0148	BARCL_0146	Pantothenate kinase.	Homologs of previously reported genes of unknown function.	0.487
coaA	ansA	BARCL_0148	BARCL_0149	Pantothenate kinase.	L-asparaginase.	0.488
coaA	pepA	BARCL_0148	BARCL_0147	Pantothenate kinase.	Leucyl aminopeptidase; Belongs to the peptidase M17 family.	0.752
gcvP	aatA	BARCL_0507	BARCL_0344	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Aspartate aminotransferase A.	0.460
gcvP	ansA	BARCL_0507	BARCL_0149	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	L-asparaginase.	0.442
gcvP	glyA	BARCL_0507	BARCL_0828	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.997
gcvP	pepA	BARCL_0507	BARCL_0147	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Leucyl aminopeptidase; Belongs to the peptidase M17 family.	0.499
gcvP	polA	BARCL_0507	BARCL_0007	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.440
glyA	gcvP	BARCL_0828	BARCL_0507	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.997