thiG protein (Bartonella clarridgeiae) - STRING interaction network

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thiG

Thiamin biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (257 aa)

Predicted Functional Partners:

thiE

0.998

thiS

0.998

thiO

0.997

thiC

0.984

thiD

0.972

moeB

0.943

dxs

0.925

thiE-2

0.899

BARCL_0774

0.605

nadE

0.539

Your Current Organism:

Bartonella clarridgeiae

NCBI taxonomy Id: 696125
Other names: B. clarridgeiae 73, Bartonella clarridgeiae 73, Bartonella clarridgeiae str. 73, Bartonella clarridgeiae strain 73

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BARCL_0774	moeB	BARCL_0774	BARCL_0182	Putative cysteine desulfurase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Molybdopterin biosynthesis protein MoeB.	0.981
BARCL_0774	thiG	BARCL_0774	BARCL_0403	Putative cysteine desulfurase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Thiamin biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.605
dxs	nadE	BARCL_0430	BARCL_0856	1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.526
dxs	thiG	BARCL_0430	BARCL_0403	1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.	Thiamin biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.925
moeB	BARCL_0774	BARCL_0182	BARCL_0774	Molybdopterin biosynthesis protein MoeB.	Putative cysteine desulfurase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.981
moeB	thiC	BARCL_0182	BARCL_0406	Molybdopterin biosynthesis protein MoeB.	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.785
moeB	thiD	BARCL_0182	BARCL_0401	Molybdopterin biosynthesis protein MoeB.	Phosphomethylpyrimidine kinase.	0.768
moeB	thiE	BARCL_0182	BARCL_0402	Molybdopterin biosynthesis protein MoeB.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).	0.636
moeB	thiE-2	BARCL_0182	BARCL_1226	Molybdopterin biosynthesis protein MoeB.	Thiamine-phosphate pyrosphorylase.	0.629
moeB	thiG	BARCL_0182	BARCL_0403	Molybdopterin biosynthesis protein MoeB.	Thiamin biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.943
moeB	thiS	BARCL_0182	BARCL_0404	Molybdopterin biosynthesis protein MoeB.	Thiamine biosynthesis protein ThiS.	0.928
nadE	dxs	BARCL_0856	BARCL_0430	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.	0.526
nadE	thiC	BARCL_0856	BARCL_0406	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.496
nadE	thiG	BARCL_0856	BARCL_0403	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	Thiamin biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.539
thiC	moeB	BARCL_0406	BARCL_0182	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Molybdopterin biosynthesis protein MoeB.	0.785
thiC	nadE	BARCL_0406	BARCL_0856	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.496
thiC	thiD	BARCL_0406	BARCL_0401	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Phosphomethylpyrimidine kinase.	0.997
thiC	thiE	BARCL_0406	BARCL_0402	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).	0.957
thiC	thiE-2	BARCL_0406	BARCL_1226	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Thiamine-phosphate pyrosphorylase.	0.777
thiC	thiG	BARCL_0406	BARCL_0403	Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Thiamin biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.984

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