Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mrcAPenicillin-binding protein 1a. (805 aa)    
Predicted Functional Partners:
ftsI
Peptidoglycan synthetase FtsI.
  
 
 0.975
AEI88745.1
Peptidoglycan glycosyltransferase.
  
 
 0.968
mrcB
Membrane carboxypeptidase.
 
 
0.948
dacB
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase.
     
 0.917
dacC-2
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.912
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
       0.773
ddlA
D-alanine-D-alanine ligase; Cell wall formation; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
  
 0.747
AEI88844.1
Hypothetical protein; Belongs to the BolA/IbaG family.
       0.556
pabC
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
   
 0.547
AEI88847.1
Membrane protein.
       0.487
Your Current Organism:
Midichloria mitochondrii
NCBI taxonomy Id: 696127
Other names: C. Midichloria mitochondrii IricVA, Candidatus Midichloria mitochondrii IricVA, Candidatus Midichloria mitochondrii str. IricVA, Candidatus Midichloria mitochondrii strain IricVA, Midichloria mitochondrii IricVA
Server load: low (30%) [HD]