folP protein (Midichloria mitochondrii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

folP

Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (262 aa)

Predicted Functional Partners:

folK

0.999

folE

0.998

floB

0.998

folC

0.997

ribH

0.646

pabC

0.594

hscA

0.532

dnaK

0.532

AEI89476.1

0.529

folD

0.522

Your Current Organism:

Midichloria mitochondrii

NCBI taxonomy Id: 696127
Other names: C. Midichloria mitochondrii IricVA, Candidatus Midichloria mitochondrii IricVA, Candidatus Midichloria mitochondrii str. IricVA, Candidatus Midichloria mitochondrii strain IricVA, Midichloria mitochondrii IricVA

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEI89476.1	dnaK	midi_01200	midi_01215	Putative ABC transporter ATP-binding protein.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.505
AEI89476.1	folE	midi_01200	midi_00987	Putative ABC transporter ATP-binding protein.	GTP cyclohydrolase I.	0.455
AEI89476.1	folP	midi_01200	midi_00935	Putative ABC transporter ATP-binding protein.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.529
AEI89476.1	hscA	midi_01200	midi_00332	Putative ABC transporter ATP-binding protein.	Chaperone protein, HscA.	0.505
dnaK	AEI89476.1	midi_01215	midi_01200	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Putative ABC transporter ATP-binding protein.	0.505
dnaK	folE	midi_01215	midi_00987	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	GTP cyclohydrolase I.	0.562
dnaK	folP	midi_01215	midi_00935	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.532
floB	folC	midi_01001	midi_00672	Putative dihydroneopterin aldolase.	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	0.669
floB	folD	midi_01001	midi_00572	Putative dihydroneopterin aldolase.	Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.477
floB	folE	midi_01001	midi_00987	Putative dihydroneopterin aldolase.	GTP cyclohydrolase I.	0.994
floB	folK	midi_01001	midi_00936	Putative dihydroneopterin aldolase.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	0.998
floB	folP	midi_01001	midi_00935	Putative dihydroneopterin aldolase.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.998
floB	ribH	midi_01001	midi_00862	Putative dihydroneopterin aldolase.	Riboflavin synthase beta-chain; Belongs to the DMRL synthase family.	0.500
folC	floB	midi_00672	midi_01001	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	Putative dihydroneopterin aldolase.	0.669
folC	folD	midi_00672	midi_00572	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.886
folC	folE	midi_00672	midi_00987	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	GTP cyclohydrolase I.	0.669
folC	folK	midi_00672	midi_00936	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	0.727
folC	folP	midi_00672	midi_00935	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.997
folC	ribH	midi_00672	midi_00862	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	Riboflavin synthase beta-chain; Belongs to the DMRL synthase family.	0.476
folD	floB	midi_00572	midi_01001	Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Putative dihydroneopterin aldolase.	0.477

page 1 of 3

Server load: low (40%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About