STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsmIUroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (298 aa)    
Predicted Functional Partners:
AEG58413.1
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: drm:Dred_0060 DNA polymerase III, delta prime subunit.
 
     0.889
AEG58414.1
PFAM: PSP1 domain protein; KEGG: drm:Dred_0061 PSP1 domain-containing protein.
  
    0.886
AEG58415.1
PFAM: protein of unknown function DUF972; KEGG: drm:Dred_0062 hypothetical protein.
  
    0.867
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
    0.815
AEG58411.1
PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: drm:Dred_0058 Orn/Lys/Arg decarboxylase, major region.
       0.715
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
  
   
 0.696
rlmH
Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
 
   
 0.679
AEG60556.1
Sun protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. Belongs to the NusB family.
     
 0.616
AEG59671.1
RNA methyltransferase, TrmA family; KEGG: drm:Dred_2261 RNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
 
  
 0.614
rsmG
Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
 
   
 0.604
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
Server load: low (24%) [HD]