STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58458.1PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: drm:Dred_0089 peptidase S8/S53 subtilisin kexin sedolisin. (360 aa)    
Predicted Functional Partners:
AEG58457.1
KEGG: drm:Dred_0088 hypothetical protein.
       0.671
AEG58632.1
PFAM: S-layer domain-containing protein; KEGG: dae:Dtox_3478 S-layer domain protein.
 
      0.550
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
 
  
 0.522
AEG58459.1
KEGG: drm:Dred_0090 hypothetical protein.
       0.469
AEG58456.1
KEGG: mpd:MCP_0336 hypothetical protein.
       0.445
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.431
AEG59600.1
Hypothetical protein.
   
 
 0.416
AEG60570.1
PFAM: Collagen triple helix repeat-containing protein; KEGG: bcq:BCQ_4541 collagen triple helix repeat domain protein.
   
 
 0.416
AEG60764.1
KEGG: cce:Ccel_3349 hypothetical protein.
   
 
 0.416
AEG60771.1
TIGRFAM: Exosporium BclB-like; KEGG: aac:Aaci_2505 collagen triple helix repeat protein.
   
 
 0.416
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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