STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58470.1PFAM: protein of unknown function DUF39; KEGG: drm:Dred_0101 hypothetical protein. (399 aa)    
Predicted Functional Partners:
AEG58471.1
PFAM: NIL domain; KEGG: drm:Dred_0102 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
  
  0.995
AEG58472.1
PFAM: ApbE family lipoprotein; KEGG: drm:Dred_0103 hypothetical protein.
 
   
 0.965
AEG59812.1
PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: drm:Dred_2207 homocysteine S-methyltransferase.
    
 0.952
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
    
  0.907
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
  0.900
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.900
AEG60092.1
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: hmo:HM1_0096 O-acetylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
     
  0.900
AEG60761.1
PFAM: Methionine synthase vitamin-B12 independent; KEGG: cbe:Cbei_2330 methionine synthase, vitamin-B12 independent.
     
  0.900
AEG61142.1
KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein.
     
  0.900
AEG59042.1
KEGG: drm:Dred_2871 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.804
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
Server load: low (20%) [HD]