STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58482.1Stage V sporulation protein T; KEGG: drm:Dred_0113 AbrB family transcriptional regulator; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain-containing protein. (186 aa)    
Predicted Functional Partners:
AEG61883.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: drm:Dred_3145 regulatory protein, DeoR.
  
  
 0.906
AEG58489.1
KEGG: drm:Dred_0118 YabP family protein; TIGRFAM: sporulation protein YabP; PFAM: YabP family protein.
 
     0.870
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.858
AEG61640.1
Stage II sporulation protein R; KEGG: drm:Dred_0458 pro-sigma-E processing factor spoIIR; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
  
   
 0.857
AEG61301.1
KEGG: drm:Dred_1056 hypothetical protein; TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase.
  
   
 0.848
AEG58495.1
SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: drm:Dred_0124 phosphoprotein phosphatase; PFAM: Stage II sporulation protein E.
 
   
 0.831
AEG59347.1
PFAM: Sporulation initiation factor Spo0A; KEGG: hmo:HM1_0304 stage 0 sporulation protein A.
  
   
 0.831
AEG61271.1
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.826
AEG61539.1
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
    0.804
AEG61229.1
Manually curated; TIGRFAM: stage V sporulation protein AD; KEGG: drm:Dred_1107 stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein.
  
   
 0.802
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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