STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58494.1PFAM: Ppx/GppA phosphatase; KEGG: drm:Dred_0123 Ppx/GppA phosphatase. (296 aa)    
Predicted Functional Partners:
AEG61476.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.930
AEG61110.1
Hypothetical protein; KEGG: cts:Ctha_1162 Ppx/GppA phosphatase.
 
  
  0.925
AEG61113.1
PFAM: Ppx/GppA phosphatase; metal-dependent phosphohydrolase HD sub domain; KEGG: drm:Dred_1179 Ppx/GppA phosphatase.
  
  
 
0.923
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
    0.647
AEG58495.1
SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: drm:Dred_0124 phosphoprotein phosphatase; PFAM: Stage II sporulation protein E.
       0.577
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
     
 0.482
AEG58493.1
PFAM: RNA binding S1 domain protein; KEGG: drm:Dred_0122 RNA-binding S1 domain-containing protein.
       0.441
AEG59276.1
PFAM: protein of unknown function DUF344; KEGG: tai:Taci_0333 protein of unknown function DUF344.
 
  
 0.422
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.405
AEG58492.1
PFAM: Septum formation initiator; KEGG: drm:Dred_0121 septum formation initiator.
  
  
 0.404
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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