STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58495.1SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: drm:Dred_0124 phosphoprotein phosphatase; PFAM: Stage II sporulation protein E. (820 aa)    
Predicted Functional Partners:
AEG61540.1
Peptidase U4 sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.960
AEG61640.1
Stage II sporulation protein R; KEGG: drm:Dred_0458 pro-sigma-E processing factor spoIIR; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
  
   
 0.894
AEG61883.1
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: drm:Dred_3145 regulatory protein, DeoR.
  
   
 0.883
AEG61538.1
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.860
AEG61301.1
KEGG: drm:Dred_1056 hypothetical protein; TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase.
  
   
 0.841
AEG58482.1
Stage V sporulation protein T; KEGG: drm:Dred_0113 AbrB family transcriptional regulator; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain-containing protein.
 
   
 0.831
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.826
AEG61144.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.825
AEG61233.1
KEGG: drm:Dred_1103 anti-sigma-factor antagonist; TIGRFAM: anti-sigma F factor antagonist; anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
  
  
 0.822
AEG58489.1
KEGG: drm:Dred_0118 YabP family protein; TIGRFAM: sporulation protein YabP; PFAM: YabP family protein.
 
     0.821
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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