STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58516.1PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: drm:Dred_0148 oxidoreductase FAD/NAD(P)-binding subunit. (277 aa)    
Predicted Functional Partners:
AEG58515.1
KEGG: drm:Dred_0147 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
 0.972
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.958
AEG58508.1
KEGG: drm:Dred_0147 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
 0.934
AEG58514.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: drm:Dred_0146 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
   
 0.917
AEG58513.1
KEGG: dae:Dtox_1278 methyl-viologen-reducing hydrogenase delta subunit; manually curated; PFAM: methyl-viologen-reducing hydrogenase delta subunit.
 
 
 0.845
AEG58507.1
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: drm:Dred_0146 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
   
 0.844
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.727
AEG58511.1
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: drm:Dred_0143 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
  
 0.726
pyrB
TIGRFAM: aspartate carbamoyltransferase; KEGG: drm:Dred_1681 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.724
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.723
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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