STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58522.1PFAM: asparagine synthase; KEGG: drm:Dred_0151 PP-loop domain-containing protein. (270 aa)    
Predicted Functional Partners:
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
 0.975
AEG59752.1
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: cbe:Cbei_0561 NCAIR mutase (PurE)-related protein.
 
  
 0.974
AEG61575.1
PFAM: Protein of unknown function DUF2088; KEGG: dae:Dtox_0989 hypothetical protein.
 
  
 0.915
AEG58523.1
PFAM: thioesterase superfamily protein; KEGG: drm:Dred_0152 thioesterase superfamily protein.
       0.781
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
    0.710
AEG60660.1
KEGG: tpd:Teth39_1977 hypothetical protein.
 
  
 0.669
AEG59271.1
KEGG: drm:Dred_2565 cobalt ABC transporter, inner membrane subunit CbiQ; TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein.
  
    0.658
AEG59269.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: drm:Dred_2567 cobalamin (vitamin B12) biosynthesis CbiM protein.
  
    0.594
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.594
AEG60929.1
PFAM: PP-loop domain protein; KEGG: drm:Dred_1321 PP-loop domain-containing protein; Belongs to the TtcA family.
 
    0.579
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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