STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
birAbiotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (328 aa)    
Predicted Functional Partners:
AEG61292.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.992
AEG61293.1
KEGG: drm:Dred_1064 pyruvate carboxylase subunit B; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein.
 
 
 
 0.974
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.972
AEG59899.1
Radical SAM domain protein; KEGG: drm:Dred_2151 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
 
 0.962
AEG60441.1
SMART: Elongator protein 3/MiaB/NifB; KEGG: clj:CLJU_c22770 radical SAM domain-containing protein.
  
 
 0.962
AEG59024.1
PFAM: peptidase M22 glycoprotease; KEGG: drm:Dred_2887 peptidase M22, glycoprotease.
 
    0.961
tadA
CMP/dCMP deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.960
AEG58545.1
PFAM: BioY protein; KEGG: drm:Dred_0169 BioY protein.
 
   
 0.920
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.894
AEG61109.1
KEGG: drm:Dred_1180 exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
  
    0.887
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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