node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEG58555.1 | clpB | Desru_0258 | Desru_0259 | KEGG: tjr:TherJR_0927 hypothetical protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.723 |
AEG58555.1 | dnaJ | Desru_0258 | Desru_0257 | KEGG: tjr:TherJR_0927 hypothetical protein. | Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.853 |
AEG58555.1 | dnaK | Desru_0258 | Desru_0256 | KEGG: tjr:TherJR_0927 hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.717 |
AEG58560.1 | AEG58969.1 | Desru_0263 | Desru_0684 | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | KEGG: adg:Adeg_0813 hypothetical protein. | 0.890 |
AEG58560.1 | AEG61951.1 | Desru_0263 | Desru_3751 | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | KEGG: tmt:Tmath_0071 StbA family protein. | 0.890 |
AEG58560.1 | dnaJ | Desru_0263 | Desru_0257 | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.853 |
AEG58560.1 | dnaK | Desru_0263 | Desru_0256 | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.926 |
AEG58560.1 | dnaK-2 | Desru_0263 | Desru_1137 | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.926 |
AEG58560.1 | groL | Desru_0263 | Desru_0758 | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.706 |
AEG58560.1 | grpE | Desru_0263 | Desru_1136 | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.856 |
AEG58560.1 | htpG | Desru_0263 | Desru_2563 | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp90-like protein; Molecular chaperone. Has ATPase activity. | 0.809 |
AEG58969.1 | AEG58560.1 | Desru_0684 | Desru_0263 | KEGG: adg:Adeg_0813 hypothetical protein. | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.890 |
AEG58969.1 | clpB | Desru_0684 | Desru_0259 | KEGG: adg:Adeg_0813 hypothetical protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.890 |
AEG58969.1 | dnaJ | Desru_0684 | Desru_0257 | KEGG: adg:Adeg_0813 hypothetical protein. | Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.921 |
AEG58969.1 | groL | Desru_0684 | Desru_0758 | KEGG: adg:Adeg_0813 hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.777 |
AEG58969.1 | grpE | Desru_0684 | Desru_1136 | KEGG: adg:Adeg_0813 hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.931 |
AEG58969.1 | htpG | Desru_0684 | Desru_2563 | KEGG: adg:Adeg_0813 hypothetical protein. | Heat shock protein Hsp90-like protein; Molecular chaperone. Has ATPase activity. | 0.949 |
AEG61951.1 | AEG58560.1 | Desru_3751 | Desru_0263 | KEGG: tmt:Tmath_0071 StbA family protein. | KEGG: drm:Dred_0180 ATPase; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.890 |
AEG61951.1 | clpB | Desru_3751 | Desru_0259 | KEGG: tmt:Tmath_0071 StbA family protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.890 |
AEG61951.1 | dnaJ | Desru_3751 | Desru_0257 | KEGG: tmt:Tmath_0071 StbA family protein. | Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.921 |