STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58555.1KEGG: tjr:TherJR_0927 hypothetical protein. (99 aa)    
Predicted Functional Partners:
dnaJ
Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...]
 
     0.853
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
       0.723
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
     0.717
AEG59273.1
KEGG: tjr:TherJR_0533 addiction module toxin, RelE/StbE family; TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system.
  
     0.618
AEG61648.1
PFAM: Nitrogenase iron-iron accessory protein AnfO; KEGG: drm:Dred_2813 hypothetical protein.
  
     0.612
AEG60781.1
PFAM: Nitrogenase iron-iron accessory protein AnfO; KEGG: drm:Dred_2813 hypothetical protein.
  
     0.556
AEG59499.1
KEGG: dae:Dtox_0663 hypothetical protein.
  
     0.554
AEG61250.1
KEGG: drm:Dred_1094 hypothetical protein.
  
     0.519
AEG58342.1
KEGG: dae:Dtox_0495 hypothetical protein.
  
     0.514
AEG58747.1
KEGG: dae:Dtox_2669 hypothetical protein.
  
     0.478
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.