STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58634.1RNA polymerase sigma factor, sigma-70 family; KEGG: cdl:CDR20291_0581 putative transcriptional regulator; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2. (170 aa)    
Predicted Functional Partners:
AEG58633.1
KEGG: gct:GC56T3_0630 toxin secretion/phage lysis holin; TIGRFAM: toxin secretion/phage lysis holin; PFAM: Holin toxin secretion/phage lysis.
  
    0.754
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.553
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.484
AEG59649.1
PFAM: Protein of unknown function DUF2275, transmembrane; KEGG: drm:Dred_0040 putative transmembrane anti-sigma factor.
  
 
 0.484
AEG60672.1
KEGG: hmo:HM1_1689 hypothetical protein.
  
 
 0.484
AEG58632.1
PFAM: S-layer domain-containing protein; KEGG: dae:Dtox_3478 S-layer domain protein.
       0.466
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.465
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.438
AEG61376.1
KEGG: drm:Dred_2741 phospholipase C zinc-binding protein; PFAM: phospholipase C zinc-binding protein; SMART: phospholipase C zinc-binding protein.
  
     0.435
AEG58892.1
KEGG: cbi:CLJ_B0745 hypothetical protein.
  
     0.422
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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