STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58643.1PFAM: Radical SAM domain protein; KEGG: drm:Dred_0270 radical SAM domain-containing protein. (328 aa)    
Predicted Functional Partners:
AEG58642.1
PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: drm:Dred_0269 hypothetical protein.
 
     0.941
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
       0.518
AEG58904.1
PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; KEGG: drm:Dred_1495 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.496
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
       0.491
AEG58761.1
KEGG: drm:Dred_2750 formate C-acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
  
  
 0.452
AEG58795.1
KEGG: cdl:CDR20291_3143 putative formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
  
  
 0.452
cutC
Pyruvate formate-lyase PFL; Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde. Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
  
  
 0.452
AEG60394.1
TIGRFAM: pyruvate formate-lyase; KEGG: aoe:Clos_2688 pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
  
  
 0.452
AEG60408.1
TIGRFAM: formate acetyltransferase; KEGG: drm:Dred_0039 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical.
  
  
 0.452
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
       0.445
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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