AEG58739.1 protein (Desulfotomaculum ruminis)

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AEG58739.1

VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (411 aa)

Predicted Functional Partners:

AEG59600.1

0.695

AEG58738.1

0.450

AEG60981.1

0.418

prmC

0.416

rplP

0.412

AEG60570.1

0.409

Your Current Organism:

Desulfotomaculum ruminis

NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEG58738.1	AEG58739.1	Desru_0450	Desru_0451	PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: amt:Amet_1540 YbaK/prolyl-tRNA synthetase associated region.	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.450
AEG58739.1	AEG58738.1	Desru_0451	Desru_0450	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: amt:Amet_1540 YbaK/prolyl-tRNA synthetase associated region.	0.450
AEG58739.1	AEG59600.1	Desru_0451	Desru_1326	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Hypothetical protein.	0.695
AEG58739.1	AEG60570.1	Desru_0451	Desru_2327	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	PFAM: Collagen triple helix repeat-containing protein; KEGG: bcq:BCQ_4541 collagen triple helix repeat domain protein.	0.409
AEG58739.1	AEG60981.1	Desru_0451	Desru_2763	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	S-layer domain-containing protein; KEGG: pjd:Pjdr2_0886 cell wall/surface repeat protein; PFAM: S-layer domain-containing protein; Fibronectin type III domain protein; SMART: Immunoglobulin subtype; Immunoglobulin C2 type; Fibronectin type III domain protein.	0.418
AEG58739.1	prmC	Desru_0451	Desru_3705	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.	0.416
AEG58739.1	rplP	Desru_0451	Desru_0305	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.	0.412
AEG59600.1	AEG58739.1	Desru_1326	Desru_0451	Hypothetical protein.	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.695
AEG60570.1	AEG58739.1	Desru_2327	Desru_0451	PFAM: Collagen triple helix repeat-containing protein; KEGG: bcq:BCQ_4541 collagen triple helix repeat domain protein.	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.409
AEG60981.1	AEG58739.1	Desru_2763	Desru_0451	S-layer domain-containing protein; KEGG: pjd:Pjdr2_0886 cell wall/surface repeat protein; PFAM: S-layer domain-containing protein; Fibronectin type III domain protein; SMART: Immunoglobulin subtype; Immunoglobulin C2 type; Fibronectin type III domain protein.	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.418
prmC	AEG58739.1	Desru_3705	Desru_0451	protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.416
rplP	AEG58739.1	Desru_0305	Desru_0451	Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.	VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.412

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