STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58739.1VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (411 aa)    
Predicted Functional Partners:
AEG59600.1
Hypothetical protein.
  
 
 0.734
AEG60981.1
S-layer domain-containing protein; KEGG: pjd:Pjdr2_0886 cell wall/surface repeat protein; PFAM: S-layer domain-containing protein; Fibronectin type III domain protein; SMART: Immunoglobulin subtype; Immunoglobulin C2 type; Fibronectin type III domain protein.
  
 
 0.492
AEG60570.1
PFAM: Collagen triple helix repeat-containing protein; KEGG: bcq:BCQ_4541 collagen triple helix repeat domain protein.
  
 
 0.485
AEG58738.1
PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: amt:Amet_1540 YbaK/prolyl-tRNA synthetase associated region.
       0.450
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.431
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
  
  
 0.431
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
     0.417
AEG60764.1
KEGG: cce:Ccel_3349 hypothetical protein.
   
 
 0.416
AEG60771.1
TIGRFAM: Exosporium BclB-like; KEGG: aac:Aaci_2505 collagen triple helix repeat protein.
   
 
 0.416
AEG60903.1
PFAM: copper amine oxidase-like domain-containing protein; KEGG: cce:Ccel_0901 copper amine oxidase domain protein.
   
 
 0.416
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.