STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG58993.1PFAM: cell divisionFtsK/SpoIIIE; KEGG: dae:Dtox_3724 cell divisionFtsK/SpoIIIE. (423 aa)    
Predicted Functional Partners:
AEG58994.1
Hypothetical protein; Manually curated; KEGG: dae:Dtox_3725 hypothetical protein.
       0.801
AEG59003.1
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: drm:Dred_0893 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
  
  
 0.690
AEG62092.1
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: drm:Dred_3320 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
  
  
 0.687
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.678
AEG58995.1
KEGG: dae:Dtox_3726 hypothetical protein.
       0.668
AEG61548.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
   
 
 0.662
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
  
 0.657
AEG59338.1
KEGG: drm:Dred_2510 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
  
  
 0.634
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.596
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
   
 0.555
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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