STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG59019.1PemK family protein; Toxic component of a type II toxin-antitoxin (TA) system. (116 aa)    
Predicted Functional Partners:
AEG59018.1
KEGG: drm:Dred_2895 CopG family transcriptional regulator.
  
 
 0.987
AEG60920.1
KEGG: drm:Dred_1332 hypothetical protein.
  
 
 0.848
AEG59020.1
PFAM: peptidase C26; KEGG: drm:Dred_2893 peptidase C26.
       0.742
AEG58557.1
PFAM: Firmicute transcriptional repressor of class III stress genes; KEGG: drm:Dred_0177 Firmicute transcriptional repressor of class III stress genes; Belongs to the CtsR family.
  
     0.609
AEG59017.1
KEGG: drm:Dred_2896 acetolactate synthase 3 regulatory subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.
       0.609
AEG59021.1
PFAM: amidohydrolase; KEGG: drm:Dred_2892 amidohydrolase.
       0.609
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.601
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
     
 0.600
AEG58849.1
KEGG: pth:PTH_2207 amino acid transporters.
  
     0.489
AEG59544.1
TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: drm:Dred_2376 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
      
 0.477
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.