STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG59024.1PFAM: peptidase M22 glycoprotease; KEGG: drm:Dred_2887 peptidase M22, glycoprotease. (237 aa)    
Predicted Functional Partners:
AEG59023.1
PFAM: Uncharacterised protein family UPF0079, ATPase; KEGG: drm:Dred_2888 hypothetical protein.
 
 0.999
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
0.999
AEG59025.1
TIGRFAM: ribosomal-protein-alanine acetyltransferase; KEGG: drm:Dred_2886 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.
  
 0.991
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
    0.961
hisI
phosphoribosyl-ATP diphosphatase; KEGG: drm:Dred_2349 phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; In the N-terminal section; belongs to the PRA-CH family.
     
 0.767
AEG61904.1
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
    
 0.649
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.637
AEG61818.1
KEGG: drm:Dred_3067 phage SPO1 DNA polymerase-related protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily.
  
    0.633
AEG59338.1
KEGG: drm:Dred_2510 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
 
     0.572
AEG61188.1
CBS domain containing protein; KEGG: drm:Dred_1131 polynucleotide adenylyltransferase region; PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; phosphoesterase DHHA1; Polynucleotide adenylyltransferase region; SMART: CBS domain containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
 
 0.569
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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