STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG59045.1KEGG: dau:Daud_0468 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. (455 aa)    
Predicted Functional Partners:
AEG59046.1
Response regulator receiver; KEGG: tjr:TherJR_0652 two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver.
 
 
 0.964
AEG61085.1
LytTr DNA-binding region; KEGG: dae:Dtox_0388 two component transcriptional regulator, LytTR family; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver.
 
 
 0.863
AEG60510.1
LytTr DNA-binding region; KEGG: dae:Dtox_2766 two component transcriptional regulator, LytTR family; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver.
 
 
 0.860
AEG62002.1
Response regulator receiver; KEGG: nth:Nther_1924 two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver.
 
 
 0.860
AEG59862.1
LytTr DNA-binding region; KEGG: cpy:Cphy_1600 LytTR family two component transcriptional regulator; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver.
 
 
 0.858
AEG60901.1
LytTr DNA-binding region; KEGG: cpy:Cphy_1600 LytTR family two component transcriptional regulator; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver.
 
 
 0.857
AEG61426.1
Response regulator receiver; KEGG: dae:Dtox_3200 two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver.
 
 
 0.857
AEG60979.1
KEGG: dhd:Dhaf_0495 response regulator receiver and SARP domain protein; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; transcriptional activator domain; SMART: response regulator receiver.
 
     0.833
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
       0.718
AEG61417.1
PFAM: LytTr DNA-binding region; KEGG: dsy:DSY2527 hypothetical protein.
 
 
 0.698
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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