STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG59046.1Response regulator receiver; KEGG: tjr:TherJR_0652 two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver. (260 aa)    
Predicted Functional Partners:
AEG59045.1
KEGG: dau:Daud_0468 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
 0.964
AEG60320.1
PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; KEGG: drm:Dred_3263 histidine kinase internal region.
 
  
 0.846
AEG60901.1
LytTr DNA-binding region; KEGG: cpy:Cphy_1600 LytTR family two component transcriptional regulator; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver.
  
     0.766
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
     0.591
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
       0.584
acpS
Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.574
AEG61417.1
PFAM: LytTr DNA-binding region; KEGG: dsy:DSY2527 hypothetical protein.
  
     0.570
AEG62028.1
TIGRFAM: diguanylate cyclase; PFAM: 5TM Receptors of the LytS-YhcK type transmembrane region; GGDEF domain containing protein; KEGG: vvy:VV0692 putative regulator of cell autolysis; SMART: GGDEF domain containing protein.
 
 
 0.505
AEG60980.1
ATP-binding region ATPase domain protein; KEGG: bss:BSUW23_17900 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Diverse 7TM receptor transmembrane region; glycoside hydrolase family 2 sugar binding; response regulator receiver; histidine kinase internal region; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
  
 
 0.480
AEG59916.1
TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; KEGG: drm:Dred_2145 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
  
  
 0.444
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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