Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG59077.1ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. (351 aa)    
Predicted Functional Partners:
AEG59079.1
PFAM: Heptaprenyl diphosphate synthase component I; KEGG: ctc:CTC01025 heptaprenyl diphosphate synthase component I.
 
   
 0.927
AEG59078.1
PFAM: protein of unknown function DUF1312; KEGG: clj:CLJU_c11430 hypothetical protein.
 
     0.893
AEG59076.1
PFAM: FMN-binding domain protein; S-layer domain-containing protein; KEGG: cce:Ccel_2338 hypothetical protein.
  
  
 0.649
AEG58392.1
Cyclic nucleotide-binding protein; KEGG: pth:PTH_2806 transcriptional regulator; PFAM: cyclic nucleotide-binding; sigma-54 factor interaction domain-containing protein; SMART: cyclic nucleotide-binding.
  
  
 0.499
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.483
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
     
 0.446
AEG58801.1
NADH dehydrogenase (quinone); KEGG: pth:PTH_1378 NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
     
 0.444
AEG60634.1
KEGG: drm:Dred_1655 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
     
 0.444
AEG61188.1
CBS domain containing protein; KEGG: drm:Dred_1131 polynucleotide adenylyltransferase region; PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; phosphoesterase DHHA1; Polynucleotide adenylyltransferase region; SMART: CBS domain containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.402
Your Current Organism:
Desulfotomaculum ruminis
NCBI taxonomy Id: 696281
Other names: D. ruminis DSM 2154, Desulfotomaculum ruminis ATCC 23193, Desulfotomaculum ruminis DL, Desulfotomaculum ruminis DSM 2154, Desulfotomaculum ruminis str. DSM 2154, Desulfotomaculum ruminis strain DSM 2154
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